But sitting down with Rails 8 proper was something else. It’s recognisable, certainly - the MVC structure, the conventions, the generators are all where you’d expect them. Someone with my dusty Rails 3 experience can still find their way around and quickly throw up the basic scaffolding. But under the hood and around the edges, it’s become a very different beast.
refuse to admit it has design flaws
，更多细节参见吃瓜
“Systolic” means data flows through the array rhythmically, like a heartbeat. One matrix is pre-loaded into the cells and stays stationary. The other streams in from the left, flowing through each cell. Every cell multiplies its resident weight by the passing activation, accumulates the partial sum, and hands data to its neighbor. By the time data exits the bottom, that’s a full matrix multiply — and no intermediate values touched memory.，这一点在手游中也有详细论述
I learned to joke about the canned cherries from the Carter Administration, but more often I told people that my ingredients were from the Obama Administration—which was closer to the truth. I had no choice but to use cartons of expired frozen-egg product and petroleum-scented flour (it, like the ice cream, was stored next to the fuel drums) and, eventually, even the decades-old cherries, but I drew the line at eating Obama-era chicken. Actually, I didn’t eat much of anything. Mostly, I survived on ramen that I discovered, along with other snack foods—sleeves of Oreos, Chips Ahoy, Nature Valley granola bars—in a cabinet under the steam table. My monkey suit (black chef’s pants and a white chef’s coat) grew looser by the day.
有趣的是，Infigratinib最初于2021年获批用于胆管癌，后因适应症开发策略调整而主动撤回。如今，其有望在ACH赛道迎来“第二春”。基于其疗效和口服便利性，BridgeBio在今年的JPM大会上预测，该药Infigratinib将占据ACH治疗市场50%以上的份额。