在临床实践中，真正需要警惕的是被称为中枢性性早熟的情况。这类孩子的整个发育进程被明显加速，其主要特征包括：第二性征在短时间内迅速进展；骨龄明显超前；有时伴随明显的情绪或行为困扰。在这种情况下，青春期的提前意味着生理调控系统被异常激活，可能影响最终身高和长期身心发展。这些患儿往往需要接受血液和脑部影像检查，并使用抑制青春期的药物，将性发育推迟到合适年龄。
On Jan. 28, just before 9:30 p.m., Kim reportedly accompanied a man in his twenties into a Gangbuk motel in Seoul, and two hours later was spotted leaving the motel alone. The following day, the man was found dead on the bed.
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Each Thursday, dozens of people queue for support awaiting their arrival - and the charity says that demand is rising.，详情可参考heLLoword翻译官方下载
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